5-Fluoro-2'-deoxyuridine, 98+%, Thermo Scientific Chemicals

Description

5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Notes
Store in a cool place.Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 50-91-9
• Molecular Formula: C9H11FN2O5
• Molecular Weight (g/mol): 246.19
• MDL Number: MFCD00006530
• InChI Key: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
• Synonym: floxuridine, 2'-deoxy-5-fluorouridine, 5-fluoro-2'-deoxyuridine, 5-fluorodeoxyuridine, fluorodeoxyuridine, floxuridin, fudr, deoxyfluorouridine, fluoruridine deoxyribose, fdurd
• PubChem CID: 5790
• ChEBI: CHEBI:60761
• IUPAC Name: 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
• SMILES: OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O

• Melting Point: 148°C to 151°C
• Quantity: 500 mg
• UN Number: UN2811
• Beilstein: 2645818
• Merck Index: 14,4112
• Solubility Information: Soluble in water,alcohol,isopropyl alcohol,methanol,aqueous buffers,acetone,dimethyl sulfoxide,and ethanol. Insoluble in ether,benzene and chloroform.
• Formula Weight: 246.2
• Percent Purity: ≥98%
• Chemical Name or Material: 5-Fluoro-2'-deoxyuridine

Safety and Handling

Hazard Category	H301-H315-H319-H341
Hazard Statement	GHS H Statement H360-H341-H302 May damage fertility or the unborn child. Suspected of causing genetic defects. Harmful if swallowed.
Precautionary Statement	P201-P202-P264b-P270-P280i-P281-P301+P310-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	200-072-5
RTECSNumber	YU7535000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only