4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals

Description

Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.

Solubility
Insoluble in water. Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 15687-27-1
• Molecular Formula: C13H18O2
• Molecular Weight (g/mol): 206.29
• MDL Number: MFCD00010393
• InChI Key: HEFNNWSXXWATRW-UHFFFAOYNA-N
• Synonym: ibuprofen, 2-4-isobutylphenyl propanoic acid, motrin, brufen, nurofen, advil, dolgit, liptan, nuprin, anflagen
• PubChem CID: 3672
• ChEBI: CHEBI:5855
• IUPAC Name: 2-[4-(2-methylpropyl)phenyl]propanoic acid
• SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(O)=O

• Melting Point: 75°C to 78°C
• Boiling Point: 157°C (4 mmHg)
• Odor: Odorless
• Quantity: 25 g
• UN Number: UN3077
• Merck Index: 14,4881
• Solubility Information: Insoluble in water. Soluble in ethanol (25mg/ml),chloroform (1:1),ether (1:2),acetone (1:1.5),aqueous solutions of alkali hydroxides and carbonates,dichloromethane,methanol (50mg/ml),and ethyl acetate.
• Formula Weight: 206.29
• Percent Purity: 99%
• Chemical Name or Material: 4-Isobutyl-alpha-methylphenylacetic acid

Safety and Handling

Hazard Category	H302-H319-H335
Hazard Statement	GHS H Statement H301-H361 Toxic if swallowed. Suspected of damaging fertility or the unborn child.
Precautionary Statement	P260-P264b-P270-P271-P280i-P301+P312-P304+P340-P305+P351+P338-P312-P314-P330-P501c
DOTInformation	Transport Hazard Class: 9; Packing Group: III; Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCES, SOLID, N.O.S.
EINECSNumber	239-784-6
RTECSNumber	MU6640000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only