4-Fluorophthalic anhydride, 98%, Thermo Scientific Chemicals

Description

4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

Solubility
Soluble in sodium hydroxide.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 319-03-9
• Molecular Formula: C8H3FO3
• Molecular Weight (g/mol): 166.11
• MDL Number: MFCD00191363
• InChI Key: XVMKZAAFVWXIII-UHFFFAOYSA-N
• Synonym: 4-fluorophthalic anhydride, 5-fluoroisobenzofuran-1,3-dione, 5-fluoro-1,3-isobenzofurandione, 1,3-isobenzofurandione, 5-fluoro, 4-fluorophthalicanhydride, 4-fluorophthalic acid anhydride, 5-fluoro-1,3-dihydro-2-benzofuran-1,3-dione, 4-fluorobenzene-1,2-dicarboxylic anhydride, 5-fluoro-isobenzofuran-1,3-dione
• PubChem CID: 67572
• IUPAC Name: 5-fluoro-2-benzofuran-1,3-dione
• SMILES: FC1=CC=C2C(=O)OC(=O)C2=C1

• Melting Point: 74°C to 79°C
• Density: 1.5
• Boiling Point: 147°C to 149°C (20 mmHg)
• Quantity: 25 g
• Beilstein: 131281
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in sodium hydroxide.
• Formula Weight: 166.11
• Percent Purity: 98%
• Chemical Name or Material: 4-Fluorophthalic anhydride

Safety and Handling

Hazard Category	H302-H315-H317-H319-H334-H335
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P272-P280-P285-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P333+P313-P342+P311-P362-P501c
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only