4-(Boc-amino)phenol, 97%, Thermo Scientific Chemicals

Description

4-(Boc-amino)phenol, is used to protect amine in the solid phase synthesis of peptides, used to produce [4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-carbamic acid tert-butyl ester at ambient temperature. This reaction will need reagent imidazole and solvent dimethylformamide, CH2Cl2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(Boc-amino)phenol, is used to protect amine in the solid phase synthesis of peptides, used to produce [4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-carbamic acid tert-butyl ester at ambient temperature. This reaction will need reagent imidazole and solvent dimethylformamide, CH2Cl2.

Solubility
Slightly soluble in water.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 54840-15-2
• Molecular Formula: C11H15NO3
• Molecular Weight (g/mol): 209.245
• MDL Number: MFCD00226573
• InChI Key: YRQMBQUMJFVZLF-UHFFFAOYSA-N
• Synonym: 4-n-boc-aminophenol, tert-butyl 4-hydroxyphenyl carbamate, tert-butyl n-4-hydroxyphenyl carbamate, tert-butyl 4-hydroxyphenylcarbamate, 4-boc-amino phenol, n-boc-4-hydroxyaniline, 1,1-dimethylethyl 4-hydroxyphenyl carbamate, 4-tert-butoxycarbonylamino phenol, 4-hydroxy-phenyl-carbamic acid tert-butyl ester, carbamic acid, 4-hydroxyphenyl-, 1,1-dimethylethyl ester
• PubChem CID: 2756771
• IUPAC Name: tert-butyl N-(4-hydroxyphenyl)carbamate
• SMILES: CC(C)(C)OC(=O)NC1=CC=C(C=C1)O

• Melting Point: 143°C to 147°C
• Quantity: 25 g
• Solubility Information: Slightly soluble in water.
• Formula Weight: 209.25
• Percent Purity: 97%
• Chemical Name or Material: 4-(Boc-amino)phenol

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only