3-Butyn-1-ol, 98%, Thermo Scientific Chemicals

Description

3-butyn-1-ol is used in the study of a palladium-catalyzed coupling with beta-tetrionic acid bromide to prepare alkynyl substituted furanones. It is also used to prepare Markovnikov addition product. Further, it is used as an intermediate of an active pharmaceutical ingredient such as fexofenadine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-butyn-1-ol is used in the study of a palladium-catalyzed coupling with beta-tetrionic acid bromide to prepare alkynyl substituted furanones. It is also used to prepare Markovnikov addition product. Further, it is used as an intermediate of an active pharmaceutical ingredient such as fexofenadine.

Solubility
Miscible with alcohols and organic solvents. Immiscible with aliphatic hydrocarbon solvents.

Notes
Incompatible with strong oxidizing agents, acids, acid anhydrides and copper.

Specifications

Chemical Identifiers

• CAS: 927-74-2
• Molecular Formula: C4H6O
• Molecular Weight (g/mol): 70.091
• MDL Number: MFCD00002955
• InChI Key: OTJZCIYGRUNXTP-UHFFFAOYSA-N
• Synonym: 3-butyn-1-ol, 3-butynol, 3-butyne-1-ol, 4-hydroxy-1-butyne, 3-butynyl alcohol, 1-butyn-4-ol, 2-hydroxyethylacetylene, homopropargyl alcohol, 2-hydroxyethyl acetylene, 4-hydroxy-butyne
• PubChem CID: 13566
• ChEBI: CHEBI:27444
• IUPAC Name: but-3-yn-1-ol
• SMILES: C#CCCO

• Melting Point: -63°C
• Density: 0.927
• Boiling Point: 129°C to 130°C
• Flash Point: 36°C (96°F)
• Odor: Characteristic
• Refractive Index: 1.4405
• Linear Formula: HC≡CCH₂CH₂OH
• Quantity: 250 g
• UN Number: UN1987
• Beilstein: 773710
• Solubility Information: Miscible with alcohols and organic solvents. Immiscible with aliphatic hydrocarbon solvents.
• Formula Weight: 70.09
• Percent Purity: ≥98%
• Chemical Name or Material: 3-Butyn-1-ol

Safety and Handling

Hazard Category	H226-H302+H312-H315-H319-H335
Hazard Statement	GHS H Statement H226-H315-H319-H335 Flammable liquid and vapor. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: ALCOHOLS, N.O.S.
EINECSNumber	213-161-9
RTECSNumber	ES0710000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only