3,4-(Methylenedioxy)aniline, 98+%, Thermo Scientific Chemicals

Description

3,4-(Methylenedioxy)aniline is an pharmaceutically important aniline derivative. It undergoes N-alkylation with cyclic secondary alkylamines in the presence of Shvo catalyst to yield N-arylpyrrolidines. 3,4-(Methylenedioxy)aniline was used in the synthesis of γ-glutamylanilides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3,4-(Methylenedioxy)aniline is an pharmaceutically important aniline derivative. It undergoes N-alkylation with cyclic secondary alkylamines in the presence of Shvo catalyst to yield N-arylpyrrolidines. 3,4-(Methylenedioxy)aniline was used in the synthesis of γ-glutamylanilides.

Solubility
Slightly soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to strong acids, acid chlorides, acid anhydrides. Air & Light Sensitive. Stable under recommended storage conditions.

Specifications

Chemical Identifiers

• CAS: 14268-66-7
• Molecular Formula: C7H7NO2
• Molecular Weight (g/mol): 137.138
• MDL Number: MFCD00005832
• InChI Key: XGNXYCFREOZBOL-UHFFFAOYSA-N
• Synonym: 3,4-methylenedioxy aniline, benzo d 1,3 dioxol-5-amine, 5-amino-1,3-benzodioxole, 3,4-methylenedioxyaniline, 4-amino-1,2-methylenedioxybenzene, 5-aminobenzodioxole, methylenedioxyaniline, 2h-1,3-benzodioxol-5-amine, 1-amino-3,4-methylenedioxybenzene, 1-amino-3,4-dimethylenedioxybenzene
• PubChem CID: 84310
• IUPAC Name: 1,3-benzodioxol-5-amine
• SMILES: C1OC2=C(O1)C=C(C=C2)N

• Melting Point: 40°C to 45°C
• Boiling Point: 144°C (16 mmHg)
• Flash Point: 142°C (287°F)
• Quantity: 250 g
• UN Number: UN2811
• Beilstein: 4919
• Sensitivity: Air and light sensitive
• Solubility Information: Slightly soluble in water.
• Formula Weight: 137.14
• Percent Purity: ≥98%
• Chemical Name or Material: 3,4-(Methylenedioxy)aniline

Safety and Handling

Hazard Category	H302+H312+H332
Hazard Statement	GHS H Statement H331-H302-H312-H315-H319 Toxic if inhaled. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P312-P330-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	238-161-6
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only