3,4-Dichloroisocoumarin, 98%, Thermo Scientific Chemicals

Description

 

Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymotrypsin and Trypsin. ,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymot

Specifications

Chemical Identifiers

• CAS: 51050-59-0
• Molecular Formula: C9H4Cl2O2
• Molecular Weight (g/mol): 215.03
• MDL Number: MFCD00036960
• InChI Key: SUGXUUGGLDCZKB-UHFFFAOYSA-N
• Synonym: 3,4-dichloroisocoumarin, 3,4-dcl, 1h-2-benzopyran-1-one,3,4-dichloro, 3,4-dci, 3,4 dichloroisocoumarin, 3,4-dichloro-1h-isochromen-1-one, 3,4-dichloro-1h-2-benzopyran-1-one, 1h-2-benzopyran-1-one, 3,4-dichloro, chembl24983, 3,4-dichloro-2-benzopyran-1-one
• PubChem CID: 1609
• IUPAC Name: 3,4-dichloroisochromen-1-one
• SMILES: ClC1=C(Cl)C2=CC=CC=C2C(=O)O1

• Color: White
• Quantity: 10 mg
• UN Number: UN2811
• Beilstein: 6802625
• Solubility Information: Soluble in DMF or DMSO at a concentration of 10mM
• Formula Weight: 215.03
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: 3,4-Dichloroisocoumarin

Safety and Handling

Hazard Category	H301-H315-H319-H335
Hazard Statement	GHS H Statement H301-H315-H319-H335 Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only