2-Fluorobenzaldehyde, 97%, Thermo Scientific Chemicals

Description

2?-(2-Fluorobenzylidene)-2-hydroxybenzohydrazide was synthesized by the reaction of 2-hydroxybenzoylhydrazine with 2-fluorobenzaldehyde in ethanol. Synthesis of n-aryl indolines from 2-fluorobenzaldehyde dimethylhydrazone derivatives which is an approach to preparation of c(aryl)-n(amine) bond atropisomeric amines. The o-dialkylaminobenzaldehydes were conveniently prepared by nucleophilic displacement of the activated fluorine in 2-fluorobenzaldehyde with the required dialkylamine in hot dimethylformamide. N?-(2-Fluorobenzylidene)-2-(quinolin-8-yloxy) acetohydrazide methanol solvate in the reaction of quinolin-8-yloxyacetic acid hydrazide and 2-fluorobenzaldehyde.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2′-(2-Fluorobenzylidene)-2-hydroxybenzohydrazide was synthesized by the reaction of 2-hydroxybenzoylhydrazine with 2-fluorobenzaldehyde in ethanol. Synthesis of n-aryl indolines from 2-fluorobenzaldehyde dimethylhydrazone derivatives which is an approach to preparation of c(aryl)-n(amine) bond atropisomeric amines. The o-dialkylaminobenzaldehydes were conveniently prepared by nucleophilic displacement of the activated fluorine in 2-fluorobenzaldehyde with the required dialkylamine in hot dimethylformamide. N′-(2-Fluorobenzylidene)-2-(quinolin-8-yloxy) acetohydrazide methanol solvate in the reaction of quinolin-8-yloxyacetic acid hydrazide and 2-fluorobenzaldehyde.

Solubility
Insoluble in water.

Notes
Air Sensitive.Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, reducing agents, air, bases.

Specifications

Chemical Identifiers

• CAS: 446-52-6
• Molecular Formula: C7H5FO
• Molecular Weight (g/mol): 124.114
• MDL Number: MFCD00003302
• InChI Key: ZWDVQMVZZYIAHO-UHFFFAOYSA-N
• Synonym: o-fluorobenzaldehyde, benzaldehyde, 2-fluoro, benzaldehyde, o-fluoro, unii-7zx20dxb9z, 2-fluor-benzaldehyd, 2-fluoro-benzaldehyde, benzaldehyde, fluoro, ortho-fluorobenzaldehyde, 7zx20dxb9z, fluorobenzaldehyde
• PubChem CID: 67970
• IUPAC Name: 2-fluorobenzaldehyde
• SMILES: C1=CC=C(C(=C1)C=O)F

• Melting Point: -45°C
• Density: 1.18
• Boiling Point: 172°C to 174°C
• Flash Point: 55°C (131°F)
• Odor: Odorless
• Refractive Index: 1.522
• Quantity: 500 g
• UN Number: UN1989
• Beilstein: 507155
• Sensitivity: Air Sensitive
• Solubility Information: Insoluble in water.
• Formula Weight: 124.11
• Percent Purity: 97%
• Chemical Name or Material: 2-Fluorobenzaldehyde

Safety and Handling

Hazard Category	H226-H302-H315-H319-H335
Hazard Statement	GHS H Statement H226-H302-H315-H319-H335 Flammable liquid and vapour. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: ALDEHYDES, N.O.S.
EINECSNumber	207-171-2
RTECSNumber	CU6140000
TSCA	No
Recommended Storage	Ambient temperatures; Store under Argon

SDS

RUO – Research Use Only