2-Bromoisobutyryl bromide, 97%, Thermo Scientific Chemicals

Description

2-Bromoisobutyryl bromide is used to prepare N-protected halodienamide, which provides four- and five-membered lactams in the presence of copper(I) and a tertiary amine. Further, it is used as atom transfer radical polymerization(ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide. It is also used in preparation of polycaprolactone macroinitiators through reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Bromoisobutyryl bromide is used to prepare N-protected halodienamide, which provides four- and five-membered lactams in the presence of copper(I) and a tertiary amine. Further, it is used as atom transfer radical polymerization(ATRP) initiator for functionalization of hydroxyl groups present on the surface of graphene oxide. It is also used in preparation of polycaprolactone macroinitiators through reaction with oligomeric caprolactone diol and mesoporous silica nanoparticles with ATRP initiator anchored on the exterior surface.

Solubility
Miscible with acetone and carbon disulfide.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents and strong alkalis.

Specifications

Chemical Identifiers

• CAS: 20769-85-1
• Molecular Formula: C4H6Br2O
• Molecular Weight (g/mol): 229.899
• MDL Number: MFCD00000122
• InChI Key: YOCIJWAHRAJQFT-UHFFFAOYSA-N
• Synonym: 2-bromo-2-methylpropionyl bromide, 2-bromoisobutyryl bromide, propanoyl bromide, 2-bromo-2-methyl, bibb, 2-bromo-2-methylpropionylbromide, unii-627f9n9dya, 2-bromoisobutyrylbromide, 2-bromo-2-methyl-propionyl bromide, alpha-bromoisobutyryl bromide, 2-bromo-2-methyl-propanoyl bromide
• PubChem CID: 88685
• IUPAC Name: 2-bromo-2-methylpropanoyl bromide
• SMILES: CC(C)(C(=O)Br)Br

• Density: 1.86
• Boiling Point: 160°C to 162°C
• Flash Point: >110°C (230°F)
• Odor: Acrid
• Refractive Index: 1.5095
• Quantity: 500 g
• UN Number: UN3265
• Beilstein: 1746128
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with acetone and carbon disulfide.
• Formula Weight: 229.91
• Percent Purity: 97%
• Chemical Name or Material: 2-Bromoisobutyryl bromide

Safety and Handling

Hazard Category	H302-H314-H317-H335-H340
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P201-P202-P260-P264b-P270-P271-P272-P280g-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	244-017-3
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only