2-Bromo-4-methylaniline, 99%, Thermo Scientific Chemicals

Description

The N-(3, 5-Dichlorophenyl) naphthaldimine was obtained from the reaction of 2-hy- droxynaphthalene-l-carbaldehyde (0.01 mol) with a solution of 2-bromo-4-methylaniline (0.01 mol) in 40 ml of ethanol. Reaction of 2-bromo-4-methylaniline was quite clean, albeit 3,4-diaminotoluene was isolated just in 37% yield after flash chromatography on silica gel. The bromomethylquinoline starting material 16 was synthesized in two steps using an optimized process route by condensing 2-bromo-4-methylaniline.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
The N-(3, 5-Dichlorophenyl) naphthaldimine was obtained from the reaction of 2-hy- droxynaphthalene-l-carbaldehyde (0.01 mol) with a solution of 2-bromo-4-methylaniline (0.01 mol) in 40 ml of ethanol. Reaction of 2-bromo-4-methylaniline was quite clean, albeit 3,4-diaminotoluene was isolated just in 37% yield after flash chromatography on silica gel. The bromomethylquinoline starting material 16 was synthesized in two steps using an optimized process route by condensing 2-bromo-4-methylaniline.

Solubility
Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 583-68-6
• Molecular Formula: C7H8BrN
• Molecular Weight (g/mol): 186.052
• MDL Number: MFCD00007635
• InChI Key: UVRRJILIXQAAFK-UHFFFAOYSA-N
• Synonym: 2-bromo-p-toluidine, benzenamine, 2-bromo-4-methyl, 4-amino-3-bromotoluene, 2-bromo-4-methylbenzenamine, p-toluidine, 2-bromo, 2-bromo-4-methyl-phenylamine, 3-bromo-4-aminotoluene, 4-methyl-2-bromoaniline, 2-bromo-4-methyl aniline, 2-bromo-4-methyl-aniline
• PubChem CID: 11422
• IUPAC Name: 2-bromo-4-methylaniline
• SMILES: CC1=CC(=C(C=C1)N)Br

• Melting Point: 14°C to 16°C
• Density: 1.494
• Boiling Point: 240°C to 242°C
• Flash Point: >110°C (230°F)
• Odor: Characteristic
• Refractive Index: 1.603
• Quantity: 50 g
• UN Number: UN2810
• Beilstein: 1931711
• Solubility Information: Insoluble in water.
• Formula Weight: 186.06
• Percent Purity: 99%
• Chemical Name or Material: 2-Bromo-4-methylaniline

Safety and Handling

Hazard Category	H301+H311+H331-H315-H319-H335-H373
Hazard Statement	GHS H Statement H301-H311-H315-H319 Toxic if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P260-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P311-P312-P314-P330-P332+P313-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S.
EINECSNumber	209-515-7
RTECSNumber	XU4300000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only