2,4-Dichloro-5-methylpyrimidine, 98%, Thermo Scientific Chemicals

Description

2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

Solubility
Soluble in chloroform, ether, ethyl acetate and toluene

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 1780-31-0
• Molecular Formula: C5H4Cl2N2
• Molecular Weight (g/mol): 163.001
• MDL Number: MFCD00023197
• InChI Key: DQXNTSXKIUZJJS-UHFFFAOYSA-N
• Synonym: pyrimidine, 2,4-dichloro-5-methyl, 5-methyl-2,4-dichloropyrimidine, 2,4-dichloro-5-methyl-pyrimidine, 2,4-dichloro-5-methyl pyrimidine, 2, 4-dichloro-5-methylpyrimidine, 2,4-dichlor-5-methylpyrimidin, pubchem5288, zlchem 1254, acmc-1bsov, ksc178k6p
• PubChem CID: 74508
• IUPAC Name: 2,4-dichloro-5-methylpyrimidine
• SMILES: CC1=CN=C(N=C1Cl)Cl

• Melting Point: 26°C to 28°C
• Density: 1.39
• Boiling Point: 108°C to 109°C (11 mmHg)
• Flash Point: 113°C (235°F)
• Quantity: 250 mg
• UN Number: UN3261
• Solubility Information: Soluble in chloroform,ether,ethyl acetate and toluene
• Formula Weight: 163.01
• Percent Purity: 98%
• Chemical Name or Material: 2,4-Dichloro-5-methylpyrimidine

Safety and Handling

Hazard Category	H314-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	217-227-8
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only