1-(Trimethylsilyl)imidazole, 97%, Thermo Scientific Chemicals

Description

1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

Solubility
Miscible with most common organic solvents. It decomposes in water.

Notes
Moisture and light sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.

Specifications

Chemical Identifiers

• CAS: 18156-74-6
• Molecular Formula: C6H12N2Si
• Molecular Weight (g/mol): 140.26
• MDL Number: MFCD00005280
• InChI Key: YKFRUJSEPGHZFJ-UHFFFAOYSA-N
• Synonym: n-trimethylsilyl imidazole, 1-trimethylsilyl imidazole, 1-trimethylsilyl-1h-imidazole, tsim, 1h-imidazole, 1-trimethylsilyl, n-trimethylsilylimidazole, trimethylsilyl imidazole, 1-trimethylsilylimidazole, n-trimethylsilyl imidazol, imidazole, 1-trimethylsilyl
• PubChem CID: 28925
• ChEBI: CHEBI:85063
• IUPAC Name: imidazol-1-yl(trimethyl)silane
• SMILES: C[Si](C)(C)N1C=CN=C1

• Melting Point: -42°C
• Density: 0.956
• Boiling Point: 212°C
• Flash Point: 18°C (64°F)
• Odor: Weak
• Refractive Index: 1.4765
• Quantity: 250 g
• UN Number: UN1993
• Beilstein: 606148
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with most common organic solvents. It decomposes in water.
• Formula Weight: 140.26
• Percent Purity: 97%
• Chemical Name or Material: 1-(Trimethylsilyl)imidazole

Safety and Handling

Hazard Category	H225-H315-H319-H335
Hazard Statement	GHS H Statement H225-H315-H319-H335 Highly flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
EINECSNumber	242-040-3
RTECSNumber	NI8700000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only