1-Propylphosphonic acid cyclic anhydride, 50+% soln. in DMF, Thermo Scientific Chemicals

Description

1-Propylphosphonic acid cyclic anhydride is used in the synthesis of N-acyloxythiazole-2(3H)-thiones. It is also used to promote the synthesis of hydroxamic acids from carboxylic acids. Further, it is employed as an efficient promoter for the Lossen rearrangement to synthesis urea and carbamate derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Propylphosphonic acid cyclic anhydride is used in the synthesis of N-acyloxythiazole-2(3H)-thiones. It is also used to promote the synthesis of hydroxamic acids from carboxylic acids. Further, it is employed as an efficient promoter for the Lossen rearrangement to synthesis urea and carbamate derivatives.

Solubility
Miscible with dichloromethane, dioxane, terahydrofuran, polar and aprotic organic solvents.

Notes
Moisture sensitive. Incompatible withstrong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 68957-94-8
• Molecular Formula: C9H21O6P3
• Molecular Weight (g/mol): 318.182
• MDL Number: MFCD00006583
• InChI Key: PAQZWJGSJMLPMG-UHFFFAOYSA-N
• Synonym: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide, 1-propanephosphonic acid cyclic anhydride, 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane 2,4,6-trioxide, unii-i6egd8839n, 1,3,5,2,4,6-trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide, propane phosphonic acid anhydride, 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane 2,4,6-trioxide, 1-propanephosphonic anhydride in thf, 2,4,6-tri-n-propyl-2,4,6-trioxo-1,3,5,2,4,6-trioxatriphosphorinane, 1-propanephosphonic anhydride in toluene, t3p
• PubChem CID: 111923
• IUPAC Name: 2,4,6-tripropyl-1,3,5,2$l^{5},4$l^{5},6$l^{5}-trioxatriphosphinane 2,4,6-trioxide
• SMILES: CCCP1(=O)OP(=O)(OP(=O)(O1)CCC)CCC

• Density: 1.09
• Boiling Point: 153°C
• Flash Point: 62°C (143°F)
• Refractive Index: 1.4505
• Quantity: 50 g
• UN Number: UN3265
• Beilstein: 5079255
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with dichloromethane,dioxane,terahydrofuran,polar and aprotic organic solvents.
• Formula Weight: 318.19
• Concentration or Composition (by Analyte or Components): ≥50% soln. in DMF
• Chemical Name or Material: 1-Propylphosphonic acid cyclic anhydride

Safety and Handling

Hazard Category	H226-H314-H332-H360D
Hazard Statement	GHS H Statement H360-H314-H332-H227 May damage fertility or the unborn child. Causes severe skin burns and eye damage. Harmful if inhaled. Combustible liquid.
Precautionary Statement	P201-P202-P210-P233-P240-P241-P242-P243-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	422-210-5
TSCA	No
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only