1-Bromo-3-chloropropane, 99%, Thermo Scientific Chemicals

Description

1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.

Solubility
Miscible with alcohols, chlorofom and ether. Immiscible with water.

Notes
Incompatible with strong oxidizing, reducing agents, amines, nitrides, azo/diazo compounds, alkali metals and epoxides.

Specifications

Chemical Identifiers

• CAS: 109-70-6
• Molecular Formula: C3H6BrCl
• Molecular Weight (g/mol): 157.435
• MDL Number: MFCD00000998
• InChI Key: MFESCIUQSIBMSM-UHFFFAOYSA-N
• Synonym: trimethylene chlorobromide, 1-chloro-3-bromopropane, 3-bromopropyl chloride, 3-chloropropyl bromide, propane, 1-bromo-3-chloro, 3-chloro-1-bromopropane, 3-bromo-1-chloropropane, trimethylene bromide chloride, 1,3-chbp, 1,3-chlorbromopropane
• PubChem CID: 8006
• IUPAC Name: 1-bromo-3-chloropropane
• SMILES: C(CCl)CBr

• Melting Point: -59°C
• Density: 1.598
• Boiling Point: 142°C to 145°C
• Flash Point: >140°C (284°F)
• Refractive Index: 1.4855
• Quantity: 250 g
• UN Number: UN2688
• Beilstein: 605278
• Solubility Information: Miscible with alcohols,chlorofom and ether. Immiscible with water.
• Formula Weight: 157.44
• Percent Purity: 99%
• Chemical Name or Material: 1-Bromo-3-chloropropane

Safety and Handling

Hazard Category	H227-H302-H331-H335-H341
Hazard Statement	GHS H Statement H331-H302 Toxic if inhaled. Harmful if swallowed.
Precautionary Statement	P201-P202-P210-P235-P261-P264b-P270-P271-P281-P301+P312-P304+P340-P308+P313-P311-P330-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: 1-BROMO-3-CHLOROPROPANE
EINECSNumber	203-697-1
RTECSNumber	TX4113000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only