1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals

Description

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.

Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.

Specifications

Chemical Identifiers

• CAS: 25952-53-8
• Molecular Formula: C8H18ClN3
• Molecular Weight (g/mol): 191.70
• MDL Number: MFCD00012503
• InChI Key: FPQQSJJWHUJYPU-UHFFFAOYSA-N
• Synonym: 1-3-dimethylaminopropyl-3-ethylcarbodiimide hydrochloride, edc.hcl, edci, edc hydrochloride, wsc hcl, edac hydrochloride, edac, hydrochloride, 1-ethyl-3-3-dimethylaminopropyl carbodiimide hydrochloride, edcl, edac hcl
• PubChem CID: 2723939
• IUPAC Name: 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;hydrochloride
• SMILES: Cl.CCN=C=NCCCN(C)C

• Melting Point: ∼113°C
• Linear Formula: CH₃CH₂N=C=N(CH₂)₃N(CH₃)₂·HCl
• Quantity: 25 g
• Beilstein: 5764110
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in acetonitrile dichloromethane,dimethylformamide,and tetrahydrofuran. Slightly soluble in water.
• Formula Weight: 191.7
• Percent Purity: ≥98%
• Chemical Name or Material: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride

Safety and Handling

Hazard Category	H302-H315-H317-H319
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P330-P333+P313-P362-P501c
DOTInformation	Hazard Class: 9; Packaging Group: III
EINECSNumber	247-361-2
RTECSNumber	FF2200000
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only