1,1,3,3-Tetramethylguanidine, 99%, Thermo Scientific Chemicals

Description

1,1,3,3-Tetramethylguanidine is employed as a polyurethane foam catalyst, as an accelerator for the syntheses of polysulfured rubber. It is also used as a strong base in the photochemical (couplers) and in the pharmaceutical (steroids) industries. It is essential for the preparation of alkyl nitriles from alkyl halides and 3'-alkylthymidines from 3'-nitrothymidines. It serves as an efficient and selective catalyst for the benzoylation of alcohols. It replaces the expensive bases 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) in organic synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,1,3,3-Tetramethylguanidine is employed as a polyurethane foam catalyst, as an accelerator for the syntheses of polysulfured rubber. It is also used as a strong base in the photochemical (couplers) and in the pharmaceutical (steroids) industries. It is essential for the preparation of alkyl nitriles from alkyl halides and 3′-alkylthymidines from 3′-nitrothymidines. It serves as an efficient and selective catalyst for the benzoylation of alcohols. It replaces the expensive bases 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) in organic synthesis.

Solubility
Miscible with water.

Notes
Air sensitive. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Keep away from sources of ignition.

Specifications

Chemical Identifiers

• CAS: 80-70-6
• Molecular Formula: C5H13N3
• Molecular Weight (g/mol): 115.18
• MDL Number: MFCD00008323
• InChI Key: KYVBNYUBXIEUFW-UHFFFAOYSA-N
• Synonym: tetramethylguanidine, n,n,n',n'-tetramethylguanidine, guanidine, n,n,n',n'-tetramethyl, tetramethyl guanidine, unii-vez101e7zu, 1,1,3,3-tetramethyl guanidine, n,n-1,1,3,3-tetramethylguanidine, vez101e7zu, 1,1,3,3-tetramethyl-guanidine, n,n,n',n'-tetramethyl-guanidine
• PubChem CID: 66460
• IUPAC Name: 1,1,3,3-tetramethylguanidine
• SMILES: CN(C)C(=N)N(C)C

• Melting Point: <-30°C
• Density: 0.918
• Boiling Point: 162°C
• Flash Point: 60°C (140°F)
• Refractive Index: 1.469
• Quantity: 500 mL
• UN Number: UN2920
• Beilstein: 969608
• Sensitivity: Air Sensitive
• Solubility Information: Miscible with water.
• Formula Weight: 115.18
• Percent Purity: 99%
• Chemical Name or Material: 1,1,3,3-Tetramethylguanidine

Safety and Handling

Hazard Category	H226-H302+H332-H314-H335
Hazard Statement	GHS H Statement H314-H318-H226-H302 Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor. Harmful if swallowed.
Precautionary Statement	P210-P233-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P331-P363-P372-P374-P380-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, FLAMMABLE, N.O.S.
EINECSNumber	201-302-7
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Argon

SDS

RUO – Research Use Only